Table 3.
Overview of current comparative oncology trials initiated by the Comparative Oncology Trials Consortium of the National Cancer Institute
| Study No. | Name | Status |
|---|---|---|
| COTC001 | Evaluation of RGD Targeted Delivery of Phage Expressing TNF-alpha to Tumor Bearing Dogs | Closed trial |
| COTC003 | Evaluation of the MTOR inhibitor Rapamycin in dogs with osteosarcoma | Closed trial |
| COTC005 | Evaluation of immunocytokine fusion protein in tumor-bearing dogs | Closed trial |
| COTC006 | Evaluation Cryobiopsy Instrumentation And Cellsave Blood Collections In Dogs With Lymphoma | Closed trial |
| COTC007a | A Pilot Study of Topotecan in Dogs with Lymphoma | Closed trial |
| COTC007b | Preclinical Comparison of Three Indenoisoquinolines Candidates in Tumor Bearing Dogs | Open |
| COTC008 | Evaluation of the mTOR inhibitor Rapamycin in Dogs with Metastatic Osteosarcoma | Closed trial |
| COTC010 | Evaluation of two immunocytokine fusion proteins in tumor bearing dogs | Closed trial |
| COTC013 | Evaluation of Orally Administered mTOR inhibitor Rapamycin in Tumor Bearing Dogs | Closed trial |
| COTC016 | A Pilot Study to Assess Feasibility of Tissue Collections and Molecular Profiling for future Comparative Oncology Personalized Medicine Studies | Closed trial |
| COTC018 | Evaluation of a novel anticancer agent in tumor bearing dogs to define its pharmacokinetic profile and biological activity | Open |