Table 3.
Top 15 and four other potentially interesting gene hits from VEGAS gene-based analysis.
| Gene | Number of SNPs | Chr. | Start position (hg19) | End position (hg19) | p-value |
|---|---|---|---|---|---|
| NMRK2 (ITGB1BP3) | 20 | 19 | 3933101 | 3942414 | 1.20E-05 |
| DAPK3 | 18 | 19 | 3958452 | 3969827 | 5.10E-05 |
| NPM3 | 4 | 10 | 103541082 | 103543170 | 0.000142 |
| EEF2 | 17 | 19 | 3976054 | 3985461 | 0.000167 |
| XRN1 | 12 | 3 | 142025449 | 142166853 | 0.000185 |
| CDK7 | 11 | 5 | 68530622 | 68573257 | 0.000206 |
| FBXL4 | 17 | 6 | 99321601 | 99395849 | 0.000257 |
| ATR | 20 | 3 | 142168077 | 142297668 | 0.000269 |
| FGF8 | 3 | 10 | 103529887 | 103535759 | 0.000294 |
| MRPS36 | 8 | 5 | 68513573 | 68525985 | 0.000423 |
| CCDC125 | 10 | 5 | 68576519 | 68616407 | 0.000424 |
| ATCAY | 33 | 19 | 3880618 | 3928080 | 0.000571 |
| KCNIP2 | 6 | 10 | 103585731 | 103603677 | 0.000637 |
| MGEA5 | 6 | 10 | 103544200 | 103578222 | 0.000654 |
| LDOC1L | 30 | 22 | 44888450 | 44894178 | 0.000664 |
| *IL1RL2 (75) | 60 | 2 | 102803433 | 102855811 | 0.0031 |
| *IL1B (80) | 20 | 2 | 113587337 | 113594356 | 0.00322 |
| *ILIA (93) | 22 | 2 | 113531492 | 113542971 | 0.00363 |
| *IL1R1 (168) | 54 | 2 | 102770401 | 102796334 | 0.00806 |
*
Ranks of these genes are mentioned in parenthesis.