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. 2014 May 9;5:50. doi: 10.3389/fpsyt.2014.00050

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Copyright © 2014 Diwadkar, Bakshi, Gupta, Pruitt, White and Eickhoff.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Significant (p < 0.05, cluster level) bilateral clusters in the dlPFC and dmPFC (insets) under the overall main effect of group in the activation analyses represent significant hypo-engagement of the structure in HGR compared to TC (graph of parameter estimates from the peak in the dlPFC). The clusters are rendered on an ascending mosaic of axial surfaces. These results imply significant hypo-engagement of the prefrontal cortex in HGR during sustained attention.