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Mean (SEM) heart rate and blood pressure following administration of MDMA or placebo as a function of dose and time. An * indicates 1.5 mg/kg MDMA significantly different from placebo (P<0.05). A § indicates 0.75 mg/kg MDMA significantly different from placebo (P<0.05). A + indicates 1.5 mg/kg significantly different from 0.75 mg/kg MDMA (P<0.05). Error bars represent SEM. Overlapping error bars were omitted for clarity.
