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. 2014 Feb 12;39(7):1664–1673. doi: 10.1038/npp.2014.13

Figure 2.

Figure 2

A repetitive stereotypic behavior is not associated with OLM impairments in BTBR mice. (a) Bar graphs shows that, as compared to B6 mice, BTBRs spend three times as much time digging (in seconds) through bedding on both training and retention trials (*P<0.05). (b) In both 5-min training and retention trials, frequency of digging bouts was greater in BTBR mice, as compared with the B6s (*P<0.05). (c) Latency to the first digging episode, measured in seconds, was shorter in BTBR mice as compared with B6s in both training and retention trials (Mann-Whitney test, ***P<0.001). (d) The mean duration (in seconds) of each digging episode did not differ between strains. (e, f) Scatter plots show the relationship of stereotypic digging behavior with OLM in individual BTBR mice. Regression analyses show that OLM retention trial discrimination indices do not correlate with the total time digging during either the training (e; Spearman correlation, P=0.82) or the retention (f; Spearman correlation, P=0.67) trial. In all cases N⩾9/group.