Figure 3.
Two-day ceftriaxone (200 mg/kg) administration abolished the increase in ethanol consumption following withdrawal in P rats (a) Two-way ANOVA #P<0.0001, Tukey's post-hoc test *P<0.0004. Ceftriaxone (200 mg/kg/day) treatment also reduced post-withdrawal ethanol consumption by Wistar rats (b) Two-way ANOVA #P=0.032, Tukey's post-hoc test *P<0.018. Note that ceftriaxone 100 mg/kg/day did not show significant effect on post withdrawal ethanol consumption in P rats (P>0.05), but with significant increase compared to saline-treated rats (P<0.05). Data is expressed as mean±SEM.