Figure 1.

Regions with abnormal white matter volume (WMV) and fractional anisotropy (FA) in patients with obsessive–compulsive disorder (OCD), and effects of medication use on the observed FA abnormalities. Regions with abnormal WMV and FA are displayed in red, and meta-regression results (slice y=−2) in green. Superior longitudinal fasciculus (light blue); cingulum bundle (dark blue); corpus callosum (yellow); anterior thalamic radiation (pink); corticospinal tract (black); frontal aslant tract (gray); frontal superior longitudinal (dark red); middle longitudinal fasciculus (green); inferior fronto-occipital fasciculus (orange); arcuate fasciculus (purple). Effect sizes used to create the meta-regression plot were extracted from the peak of maximum slope significance, and may thus overestimate the effect that would be observed in a broader region.