. 2013 Oct 9;22(6):768–775. doi: 10.1038/ejhg.2013.232

Table 1. Myosin genes and mutations in the Middle Eastern population.

Gene	Gene mutation	Protein mutation	Phenotype	Inheritance	Origin	Family	Reference
MYO3A	c.732-2A>G	Splice mutation	Late-onset, progressive NSHL	Recessive	Jewish-Iraq		⁷
	c.1777-12G>A	Splice mutation	Late-onset, progressive NSHL	Recessive	Jewish-Iraq		⁷
	c.3126T>G	p.Tyr1042*	Late-onset, progressive NSHL	Recessive	Jewish-Iraq		⁷
MYO6	c.897G>T	Splice mutation	Congenital NSHL, Hom; late-onset NSHL, Het	Semi-dominant	Arab-Palestinian	AV	Present study
	c.2777T>A	p.Leu926Gln	Congenital, NSHL	Recessive	Arab-Palestinian	QS009	Present study
MYO7A	c.29T>C	p.Val10Ala	Congenital, NSHL	Recessive	Jewish-Turkey	D79	Present study
	c.620A>G	p.Asn207Ser	Congenital, NSHL	Recessive	Jewish-Uzbekistan	D75	Present study
	c.1969C>T	p.Arg657Trp	Congenital, NSHL	Recessive	Jewish- Turkey	D79	Present study
	c.4153-2A>G	Splice mutation	Congenital, NSHL	Recessive	Arab-Palestinian	QS004 QS013	Present study
	c.6211C>T	p.Gln2071*	Congenital, NSHL	Recessive	Arab-Palestinian	QS025	Present study
	c.G6487A	p.Gly2163Ser	Congenital, NSHL	Recessive	Arab-Palestinian		²²
MYO15A	c.373delCG	p.Arg125Vfs*101	Congenital, NSHL	Recessive	Jewish-Ashkenazi		³
	c.1223C>T	p.Ala408Val	Congenital, NSHL	Recessive	Arab-Palestinian	BA	Present study
	c.4240G>A	p.Glu1414Lys	Congenital, NSHL	Recessive	Arab-Palestinian		³
	c.7545G>T	p.Asp 2403 fsX2414	Congenital, NSHL	Recessive	Arab-Palestinian		²²
	c.8183G> A	p.Arg2728His	Congenital, NSHL	Recessive	Jewish-Ashkenazi		³
	c.8467G>A	p.Asp2823Asn	Congenital, NSHL	Recessive	Jewish-Iran	1234	Present study

Abbreviation: NSHL, non-syndromic hearing loss.