Table 1. Baseline characteristics.

	CAD+	CAD−
	n=482	n=1212	P-value
Age first visit lipid clinic (years)	50.5 (11.1)	42.2 (12.3)	<0.0001
Age last visit lipid clinic (years)	57.1 (11.2)	46.6 (12.5)	<0.0001
Male gender	301 (62)	516 (42)	<0.0001
Diabetes mellitus	54 (11)	45 (4)	<0.0001
Hypertension	79 (16)	77 (6)	<0.0001
History of smoking	365 (75)	766 (63)	<0.0001
Body mass index, kg/m2	25.7±3.2	24.9±3.6	<0.0001
Family history CVD	204 (42)	607 (50)	0.005
Treatment-naive lipids levels:
Total cholesterol, mmol/l	9.6 (2.1)	9.4 (1.9)	0.146
LDL-cholesterol, mmol/l	7.0 (1.9)	7.2 (1.8)	0.152
HDL-cholesterol, mmol/l	1.1 (0.3)	1.2 (0.4)	<0.0001
Triglyceridesa, mmol/l	1.8 (1.3–2.5)	1.5 (1.0–2.0)	<0.0001
LDL-receptor mutation provenb	207 (43)	655 (54)	0.017
Age of CAD onset, years	49.1±10.7	Na	Na
Age of start statin use	48.8±11.5	40.9±12.6	<0.0001

Abbreviations: CAD, coronary artery disease; CVD, cardiovascular disease; LDL, low-density lipoprotein; HDL, high-density lipoprotein.

Values are given as number (percentage) or mean±SD unless indicated otherwise.

^aMean±interquartile range.

^bMutations of the LDL receptor that have been examined according to Umans-Eckenhausen MA et al.¹³