Table 3.
Comparison of expression change for some TFs of interest in Nfib - and Nr3c1 -knockout lungs
| |
Nfib
-KO |
Nr3c1
-KO |
||
|---|---|---|---|---|
| Gene | FC | p - value | FC | p - value |
|
Nfib |
*2.75 |
<10-5 |
2.17 |
0.001 |
|
Nr3c1 |
1.23 |
0.172 |
*3.14 |
<0.001 |
|
Nfia |
2.27 |
0.001 |
0.61 |
0.006 |
|
Snai2 |
1.72 |
<10-5 |
1.54 |
0.003 |
|
Meis2 |
1.57 |
0.023 |
2.03 |
0.012 |
| Nr2f1 | 1.83 | 0.001 | 1.66 | 0.003 |
For each knockout, the table shows the expression fold change and the associated uncorrected p-value (see Methods). The expression changes for Nfib and Nr3c1 transcripts in their respective KO (marked by an asterisk) occurs in the context of the transcripts lacking an essential exon and thus no functional protein is expressed.