Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2014 Apr 2;123(20):e110–e122. doi: 10.1182/blood-2013-08-520619

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2014 by The American Society of Hematology

PMC Copyright notice

GO analysis of transcriptional profiles from monocyte-derived and tissue resident macrophage-derived AAMs. (A) Biological processes (BPs) induced in IL-4c expanded AAM (IL-4c) relative to resident macrophages (Res). x-axis indicates the amount of statistical significance [as −log(P)] in enrichment for the indicated biological process. Arrows depict pathways of interests mentioned in the text. (B) BPs induced in Thio+IL-4c-induced AAMs relative to Thio-induced macrophages. (C) BPs induced in both monocyte- and tissue-derived AAMs. (D) Molecular function (MF) pathways induced in Thio+IL-4c-induced AAMs relative to Thio-induced macrophages. (E) Hierarchical clustering analysis of 26 unsupervised k-means clusters of genes that have similar expression profiles. The averaged expression for all the genes in each cluster is shown as a single row. The biological significance of each cluster was determined by measuring the GO term enrichment for BPs. Results shown are for individual mice.