Table 1. Powers obtained by three epistasis detection methods for three-way, four-way and five-way interactions.
Interaction order | CSE | MDR | BEAM |
---|---|---|---|
Three-way | 69 | 45 | 48 |
Four-way | 47 | 40 | 35 |
Five-way | 18 | 12 | 31 |
Abbreviations: BEAM, Bayesian epistasis association mapping; CSE, cuckoo search epistasis; MDR, multifactorial dimensionality reduction; SNP, single-nucleotide polymorphism.
Power is estimated as the proportion of the 100 replicate data sets for which the method ranks the functional SNPs as the top three, four or five SNPs.