Table 5. Adjusted adds ratios of overweight, dyslipidemia, hypertriglyceridemic waist, low total adiponectin concentration and pre‐existing coronary artery disease in patients with type 2 diabetes for ADIPOQ polymorphisms.
| ADIPOQ | N | Overweight | Dyslipidemia | HTGW | Low total Ad levels | CAD | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| OR (95% CI) | P | OR (95% CI) | P | OR (95% CI) | P | OR (95% CI) | P | OR (95% CI) | P | ||
| rs2241766 | |||||||||||
| TT | 169 | 1 | 1 | 1 | 1 | 1 | |||||
| GG/TG | 23 | 0.3 (0.1–0.9) | 0.06 | 1.6 (0.6–4.0) | 0.30 | 3.1 (1.1–9.3) | 0.04 | 0.7 (0.3–2.9) | 0.62 | 3.3 (1.3–8.7) | 0.01 |
| rs1501299 | |||||||||||
| GG | 72 | 1 | 1 | 1 | |||||||
| GT | 93 | 1.4 (0.6–3.6) | 0.46 | 1.0 (0.5–1.9) | 0.92 | 0.4 (0.1–1.2) | 0.10 | 0.6 (0.3–1.2) | 0.16 | 0.7 (0.2–1.4) | 0.32 |
| TT | 29 | 0.5 (0.2–1.4) | 0.17 | 1.7 (0.7–4.1) | 0.24 | 0.8 (0.2–2.8) | 0.69 | 0.8 (0.3–2.1) | 0.60 | 1.1 (0.4–2.9) | 0.87 |
| rs17300539 | |||||||||||
| GG | 182 | 1 | 1 | 1 | 1 | 1 | |||||
| GA/AA | 8 | 1.0 (0.1–9.0) | 0.97 | 1.3 (0.3–5.7) | 0.70 | 1.2 (0.1–10.5) | 0.28 | 1.7 (0.4–8.1) | 0.49 | 1.6 (0.3–7.1) | 0.57 |
| rs182052 | |||||||||||
| GG | 80 | 1 | 1 | 1 | 1 | 1 | |||||
| GA | 77 | 1.0 (0.4–2.3) | 0.92 | 1.1 (0.6–2.1) | 0.76 | 2.2 (0.8–5.8) | 0.12 | 0.4 (0.2–0.9) | 0.03 | 1.4 (1.7–3.0) | 0.31 |
| AA | 32 | 2.1 (0.5–7.9) | 0.26 | 0.9 (0.4–2.1) | 0.54 | 0.7 (0.1–3.5) | 0.65 | 0.3 (0.1–0.3) | 0.03 | 0.5 (0.2–1.6) | 0.27 |
Low total adiponectin (Ad): total Ad concentration <25th percentile (3.49 ng/mL). Odds ratios (OR) and 95% confidence intervals (CI) were adjusted for age and sex. Significant P‐values are presented in bold. CAD, coronary artery disease; HTGW, hypertriglyceridemic waist.