Table 3. Odds ratios (95% confidence intervals) associated with risk factors for fractures in multivariable logistic regression.
| Variables | OR (95% CI) | P‐value |
|---|---|---|
| Age (years) | 0.94 (0.83 –1.06) | 0.613 |
| Duration of diabetes (years) | 1.10 (1.02 –1.21) | 0.027 |
| HbA1c (%) | 1.11 (1.03 –1.24) | 0.047 |
| Fasting insulin (mIU/L) | 0.76 (0.44 –1.08) | 0.732 |
| Body mass index (kg/m2) | 0.78 (0.35 –1.04) | 1.034 |
| Lumber spine BMD (g/cm2) | 0.75 (0.31 –1.13) | 0.715 |
| Femoral neck BMD (g/cm2) | 0.86 (0.55 –1.12) | 0.480 |
| Parental history of fracture (%) | 0.81 (0.65 –1.07) | 0.567 |
| Presence of retinopathy (%) | 1.02 (0.83 –1.10) | 0.122 |
| Thiazolidenediones use (%) | 0.89 (0.73 –1.04) | 0.478 |
| Male sex | 0.43 (0.10 –1.15) | 1.175 |
| Active smoker (%) | 0.65 (0.39 –1.01) | 0.730 |
| Alcohol intake (%) | 0.82 (0.43 –1.08) | 0.862 |
| CRP (mg/L) | 0.97 (0.73 –1.15) | 0.186 |
| Serum folate (nmol/L) | 0.95 (0.84 –1.16) | 0.399 |
| Serum B12 (pmol/L) | 0.81 (0.42 –1.07) | 0.873 |
| Urinary ACR (mg/g) | 0.92 (0.77 –1.13) | 0.525 |
| Serum creatinine (μmol/L) | 0.78 (0.30 –1.16) | 1.042 |
| Homocysteine (μmol/L)* | 1.50 (1.14 –2.12) | 0.016 |
All values are odds ratio (OR) and 95% confidential interval (95% CI). Model Nagelkerke R2: 0.27. *Homocysteine adjusted for risk factors for fracture and determinants of homocysteine. ACR, albumin to creatinine ratio; BMD, bone mineral density; CI, confidence interval; CRP, C‐reactive protein; HbA1c, glycated hemoglobin.