Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2014 Apr 23;15:301. doi: 10.1186/1471-2164-15-301

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2014 Xie; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

PMC Copyright notice

Expression profiles of MKL1/2 and ELK4 dependent target genes in response to zymosan treatment. (A) and (B) Expressions of MKL1/2 dependent genes (Cfl1, Dstn, Vcl and Thbs1) and ELK4 dependent genes (Il10, c-fos, Egr1 and Egr3) were analyzed by Q-PCR. Thioglycollate-elicited macrophages were transfected with NS or specific siRNAs for MKL1/2 or ELK4, as indicated, and treated with or without zymosan for 1 h. (C)Srf mRNA expression in response to MKL1/2 or ELK4 knockdown under basal conditions or after treatment with zymosan for 1 h. Target gene expression is represented as the average fold change compared to NS siRNA transfected samples of three independent experiments. **p < 0.01 vs. NS; *p < 0.05 vs. NS. Error bars represent standard deviations.