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. 2014 Mar 31;2:33. doi: 10.1186/2051-5960-2-33

Table 1.

Summary of the characterization of New TDP-43 MAbs

MAb Isotype Epitope (aa) IP IB IHC ICC ELISA capture ELISA detect Human preference
211
IgG1
6-24
-
+
+
+
+
-
-
5031
IgG2a
25-181
+
+
+
+
+
+
-
138
IgG2a
182-261
+
+
+
+
+
+
+
5060
IgG2a
182-261
ND
+
+
+
+
+
-
5117
IgG2a
287-322
ND
+
+
+
+
+
-
5156
IgG2a
287-322
+
+
+
+
+
+
-
205
IgG2a
262-391
+
+
+
+
+
+
+
241
IgG1
262-391
+
+
+
+
+
+
+
5028
IgG1
262-391
+
+
+
+
+
+
-
5032
IgG1
262-391
+
+
+
+
+
+
+
5053
IgG1
262-391
ND
+
+
-
+
+
-
5056
IgG2a
261-391
+
+
+
+
+
+
-
5089
IgG2b
261-391
+
+
+
+
+
+
-
5095
IgG1
261-391
+
+
+
+
+
+
+
5104
IgG1
261-391
+
+
+
+
+
+
+
5123
IgG1
261-391
+
+
+
+
+
+
+
5101
IgG1
261-391
+
+
+
+
+
+
-
5195 IgG2a 394-414 + + + + + + -

This table summarizes the properties the new MAbs described here. New abbreviation: ND = not determined.