Table 4.
Potential haplotype interference for disease primers.
| Mutation | SNP | Frequency % (#) | Conflicting haplotype |
|---|---|---|---|
| Panel MD1 | |||
| m.8356T>C | None | ||
| m.11778G>A | None | ||
| m.3271T>C | None | ||
| m.1555A>G | None | ||
| m.8344A>G | None | ||
| m.3460G>A | None | ||
| m.7445A>G, C | 7444 | 0.47% (12) | H*, H6776, H* |
| Panel MD2 | |||
| m.14484T>C | 14 470 | 3.12% (79) | F1 |
| 14 476 | 0.91% (23) | X, H10 | |
| m.3243A>G, T | None | ||
| m.14487T>C | 14 502 | 0.59% (15) | M10, N*, X |
| m.8993T>G, C | 8994 | 2.49% (63) | L0, W, Hv |
| m.10191T>C | 10 181 | 0.83% (21) | D4b |
| m.14459G>A | None | ||
| Panel LD1 | |||
| m.11778G>A | None | ||
| m.3733G>A | None | ||
| m.10663T>C | 10 646 | 0.55% (14) | M10, M8, D, H6776, H* |
| m.14482C>G, A | 14 476 | 0.91% (23) | F1 |
| 14 470 | 0.59% (79) | X, H10 | |
| m.14495A>G | 14 502 | 0.59% (15) | |
| m.14568C>T | 14 569 | 3.63% (92) | Various |
| 14 582 | 1.03% (26) | N9a, H4 | |
| m.3460G>A | None | ||
| Panel LD2 | |||
| m.14484T>C | 14 476 | 0.91% (23) | F1 |
| 14 470 | 3.12% (79) | X, H10 | |
| m.4917A>G | 4907 | 0.55% (14) | L0, L3 |
| m.13708G>A | None | ||
| m.4216T>C | None | ||
| m.4171C>A | 4164 | 1.54% (39) | M7b |
| m.14459G>A | None |
As tested column, primer used was on the reverse strand.