Table 3. ED₅₀ Values Determined for Peptides 1, 4, and 5, Respectively, as Calculated Using Standard Nonlinear Regression Analysis of the Log Dose–Response Curve^a.

	ED50 values (mg/kg)
no.	hot-plate test	tail-flick test
1	0.25++	0.17 ** ,+, ###
4	0.40	0.27*
5	0.31	0.34

^a**hot-plate vs. tail-flick; ⁺⁺p < 0.01; ⁺p < 0.05 (1 vs. 4); ^###p < 0.001 (1 vs. 5).