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. 2014 Apr 9;10:24. doi: 10.1186/1744-8069-10-24

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Copyright © 2014 Dickie and Torsney; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License( http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver ( http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Monosynaptic C-fibre input to lamina I NK1R+ neurons. A. and B. Characterisation of primary afferent input to lamina I NK1R+ neurons receiving monosynaptic C-fibre only and monosynaptic C-fibre with polysynaptic A δ-fibre input, respectively. Left traces show examples of ESPCs evoked by dorsal root stimulation at A β- (20 μA), A δ- (100 μA) and C-fibre (500 μA) intensities, at low frequency (0.05 Hz). Each trace is an average of 3 traces. Right traces show examples of EPSCs evoked using higher-frequency stimulation (20 μA/20 Hz; 100 μA/2 Hz; 500 μA/1 Hz). Each trace comprises 20 superimposed traces.