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Sensitization of wild-type cells to amphotericin B by myriocin and its reversal by phytosphingosine (PHS). C. albicans (SC5314), C. glabrata (CG462), C. lusitaniae (CL1, CL6), and S. cerevisiae (FY4, BY4743) strains were tested for their sensitivity to AmB alone (top panels) or their sensitivity in the presence of myriocin (middle panels) or myriocin and PHS (lower panels). Comparable results were obtained from three independent experiments.
