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. 2014 Apr;58(4):2076–2083. doi: 10.1128/AAC.01936-13

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FIG 2 — Silymarin reduced fibrosis and profibrogenic cytokines in chronic S. mansoni infection. (A) Biochemical quantification of hydroxyproline. (B) Examples of images from histological sections (5 μm) of hepatic tissue stained with picrosirius from I+Veh 80D (left) and I+SIL 80D (right) used to evaluate the granuloma collagen areas. (C to E) Concentrations of IL-4 (C), IL-13 (D), and IFN-γ (E) in serum. (F) IFN-γ/IL-4 relation; (G) IFN-γ/IL-13 ratio. Results were expressed as means + SE. *, P < 0.05 for N versus I comparison; #, P < 0.05 for I versus I+SIL 50D and I+SIL 10D; ##, P < 0.05 for I+Veh 80D versus I+SIL 80D.