TABLE 1.
Distribution of different drug susceptibility patterns and genotypes among MDR-TB isolates from China
| Type | DST result | No. (%) of isolates | No. (%) of isolates of indicated genotype |
|||||
|---|---|---|---|---|---|---|---|---|
| Beijing | Modern Beijing | T | H | MANU2 | Orphan | |||
| Simple MDR-TB | INH+RIF | 65 (50.8) | 57 (52.8) | 30 (46.9) | 4 (44.5) | 1 (25.0) | 0 (0.0) | 3 (60.0) |
| Pre-XDR-TB | INH+RIF+CAP | 1 (0.8) | 0 (0.0) | 0 (0.0) | 1 (11.1) | 0 (0.0) | 0 (0.0) | 0 (0.0) |
| INH+RIF+CAP+KAN | 2 (1.6) | 2 (1.9) | 2 (3.1) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | |
| INH+RIF+OFX | 47 (36.7) | 37 (34.2) | 24 (37.5) | 3 (33.3) | 3 (75.0) | 2 (100.0) | 2 (40.0) | |
| XDR-TB | INH+RIF+OFX+CAP | 2 (1.6) | 2 (1.9) | 2 (3.1) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) |
| INH+RIF+OFX+KAN | 6 (4.6) | 5 (4.6) | 1 (1.6) | 1 (11.1) | 0 (0.0) | 0 (0.0) | 0 (0.0) | |
| INH+RIF+CAP+KAN+OFX | 5 (3.9) | 5 (4.6) | 5 (7.8) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | |
| Total | 128 (100.0) | 108 (100.0) | 64 (100.0) | 9 (100.0) | 4 (100.0) | 2 (100.0) | 5 (100.0) | |