TABLE 1.
Antimicrobial resistance and virulence factors of CTX-M-producing and non-ESBL-producing K. pneumoniae isolates
| Antimicrobial resistance or virulence factor | No. (%) of isolates |
Pa | ||
|---|---|---|---|---|
| Total (n = 98) | CTX-M-producing (n = 33) | Non-ESBL-producing (n = 65) | ||
| Resistance to antimicrobial agent | ||||
| Ampicillin | 97 (99.0) | 33 (100) | 64 (98.5) | 0.474 |
| Ceftazidime | 50 (51.0) | 31 (93.9) | 19 (29.2) | <0.001 |
| Cefotaxime | 47 (48.0) | 28 (84.8) | 19 (29.2) | <0.001 |
| Aztreonam | 42 (42.9) | 27 (81.8) | 15 (23.1) | <0.001 |
| Amikacin | 11 (11.2) | 2 (6.1) | 9 (13.8) | 0.327 |
| Gentamicin | 50 (51.0) | 33 (100) | 17 (26.2) | <0.001 |
| Ciprofloxacin | 43 (43.9) | 20 (60.6) | 23 (35.4) | 0.017 |
| Imipenem | 1 (1.0) | 1 (3) | 0 | 0.287 |
| Trimethoprim-sulfamethoxazole | 45 (45.9) | 30 (90.9) | 15 (23.8) | <0.001 |
| Piperacillin-tazobactam | 52 (53.1) | 22 (66.7) | 30 (46.2) | 0.022 |
| Virulence factor | ||||
| fimH | 98 (100) | 33 (100) | 65 (100) | |
| oxyR | 98 (100) | 33 (100) | 65 (100) | |
| ureA | 98 (100) | 33 (100) | 65 (100) | |
| kfu | 97 (99.0) | 32 (96.9) | 65 (100) | 0.330 |
| wabG | 97 (99.0) | 33 (100) | 64 (94.1) | 0.549 |
| uge | 92 (93.8) | 33 (100) | 59 (90.7) | 0.174 |
| ramA | 91 (92.8) | 31 (93.9) | 60 (92.3) | 0.579 |
| allS | 31 (31.6) | 4 (12.1) | 27 (41.5) | 0.005 |
| iutA | 29 (29.5) | 8 (24.2) | 21 (32.3) | 0.494 |
| rmpA | 24 (24.4) | 4 (12.1) | 20 (30.7) | 0.080 |
| wca | 22 (22.4) | 5 (15.1) | 17 (26.1) | 0.310 |
| cf29a | 15 (15.3) | 1 (3.0) | 14 (21.5) | 0.018 |
| magA | 13 (13.2) | 2 (6.0) | 11 (16.9) | 0.134 |
| ybtQ | 2 (2.0) | 0 | 2 (3.0) | 0.549 |
a
P values between CTX-M-producing and non-ESBL-producing K. pneumoniae isolates.