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Multidose pharmacodynamic analysis of simulated amphotericin B doses with fCmax of 0.1, 0.3, 0.6, 0.8, 1, 1.2, and 2.4 mg/liter against A. fumigatus, A. flavus, and A. terreus isolates with a modal CLSI MIC of 1 mg/liter as determined by the galactomannan index in the in vitro PK-PD model.
