. Author manuscript; available in PMC: 2015 Apr 1.

Published in final edited form as: Neurobiol Dis. 2014 Jan 11;64:118–130. doi: 10.1016/j.nbd.2014.01.001

Table 2.

Neuropathy After 6 Months of Diabetes in the Adult C57Bl/6J Mouse is Characterized by Loss of the Largest Myelinated Fibers.

Myelinated Fiber Counts	Non-Diabetic (n=7)	Diabetic (n=5)	Significance
Fiber density (/mm²)	12,888 ± 2,300	11,548 ± 1,600	NS
Fascicular Area (mm²)	1.199 ± 0.037.10⁻³	1.254 ± 0.075.10⁻³	NS
Axon Area (μm²)	33.4 ± 6.41	30.64 ± 3.53	NS
Axon Diameter (μm²)	5.47 ± 0.61	5.39 ± 0.38	NS
Myelin thickness (μm)	1.67 ± 0.09	1.52 ± 0.08	NS
g-ratio	0.61 ± 0.03	0.64 ± 0.01	NS
Ratio of fibers >10 μm Diam.	0.13	0.069	p=0.02

NS: not significant