Table 3.

Chromosomal regions achieving at least suggestive linkage (HLOD ≥ 1.86) evidence using the original, unscreened SNP set.

Chromosome location	SNP at maximum HLOD (basepair)	Original HLOD (model)	HLOD after LD screening (model)	Original NPL score	NPL score after LD screening
2p25.3-p24.1	rs792065 (5,434,974)	2.03 (rec)	1.87 (rec)	2.47	2.18
6q22.32-q24.1	rs1570056 (137,101,370)	1.98 (rec)	1.81 (rec)	1.84	1.79
6q27	rs909475 (170,655,714) [screened: rs9295417 (170,734,025)]	2.11 (dom)	0.00 (dom)	0.82	0.61
7q31.31-q32.3	rs1990790 (129,820,866) [screened: rs1419437 (126,447,341)]	2.45 (rec)	1.97 (rec)	2.12	1.88
13q12.11-q12.3	rs6490970 (24,132,738)	1.88 (rec)	1.93 (rec)	1.83	1.81
15q13.1-q14	rs8033248 (29,459,872)	5.01 (rec)	4.09 (rec)	3.43	3.11
15q14-q21.1	rs723049 (36,837,208)	4.05 (rec)	3.59 (rec)	3.31	3.14
15q21.2-q22.1	rs11856 (55,629,733)	6.59 (rec)	5.31 (rec)	4.17	4.02
15q21.1-q22.2	rs383902 (56,821,466) [screened: rs725463 (57,930,371)]	3.10 (dom)	1.49 (dom)	3.37	3.21
19q13.43	rs4801273 (63,692,085) [screened: rs964795 (63,029,177)]	2.09 (dom)	0.01 (dom)	0.09	0.17
21q22.12-q22.13	rs2032088 (37,399,200); [screened rs1016694 (38,156,688)]	3.52 (dom)	0.01 (dom)	1.28	0.72
21q22.12-q22.13	rs2835667 (37,501,784) [screened: rs1012959 (36,983,492)]	2.06 (rec)	0.10 (rec)	1.27	0.63

Note. SNPs were screened and omitted if the minor allele frequency was < 0.10, and for linkage disequilibrium.