Table 3. Overall analysis of perioperative outcomes comparing LRC and ORC.

Outcome of interest	No. of studies	No. of patients, LRC/ORC	WMD/OR (95% CI)	p-value	Study heterogeneity				Egger’s test (p value)
					Chi2	df	I2	p-value
Operating time, min	16	534/522	35.79 [16.79, 54.79]	<0.001	334.11	15	96%	<0.001	0.08
EBL, mL	16	534/522	−467.32 [−636.72, −297.91]	<0.001	465.70	15	97%	<0.001	0.11
LOS, days	16	534/522	−2.72 [−3.63, −1.80]	<0.001	38.55	15	61%	<0.001	0.35
Blood transfusion rate	9	284/281	0.20 [0.14, 0.29]†	<0.001	12.24	8	36%	0.13	0.64
Time to ambulation, days	3	118/119	−1.69 [−3.24, −0.14]	0.03	13.22	2	85%	0.001	0.14
Time to regular diet, days	15	476/470	−1.53 [−1.95, −1.11]	<0.001	256.44	14	95%	<0.001	0.01
Narcotic analgesic requirement, mg	6	140/133	−29.55 [−43.70, −15.39]	<0.001	26.05	5	81%	<0.001	0.37

CI = Confidence interval; OR = odds ratio; WMD = weighted mean difference; LRC =  laproscopic radical cystectomy; ORC =  open radical cystectomy; EBL = estimated blood loss; LOS = length of hospital stay.

^†Values of OR;

*Statistically significant results are shown in bold.