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. 2014 May 16;9(5):e97574. doi: 10.1371/journal.pone.0097574

Figure 2. RNA library for SELEX and RNA aptamer sequences.

Figure 2

(A) The sequence of the RNA pool for in vitro selection is shown. The random RNA library was produced by PCR and in vitro transcription of DNA template containing 40 random sequences. (B) The RNAs selected after the 12th round of SELEX were sequenced and grouped based on sequence similarity. Four groups of RNA aptamers were obtained (frequency is depicted in parentheses) and representative RNA sequences of each group are shown (the conserved sequences of each group are underlined).