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. Author manuscript; available in PMC: 2015 Jul 1.
Published in final edited form as: Biomaterials. 2014 Apr 4;35(20):5327–5336. doi: 10.1016/j.biomaterials.2014.03.034

Figure 4. Hierarchical clustering of gene transcripts.

Figure 4

(A) Hierarchical clustering of transcripts from non-converted PMEFs not expressing the synapsin-RFP reporter (left) and converted synapsin-RFP+ iNs (right). (B) Hierarchical clustering of expressed transcripts differentially regulated on smooth versus on 5 μm gratings topography. (C) Hierarchical clustering of expressed transcripts differentially regulated in iNs on smooth substrates (left) and on 5 μm gratings substrates (right). 20 genes expressed in iNs were found to be differentially regulated in response to the grating substrates compared to the smooth controls. (D) Quantitative, real time qPCR for Vip, Thy1 and Bmp5.