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. 2014 May 16;9(5):e97594. doi: 10.1371/journal.pone.0097594

Figure 3. VPA decreases cigarette smoke-induced neutrophil influx in BAL fluid of mice.

Figure 3

(A) Total cell numbers, (B) macrophages and (C) neutrophils in the BAL fluid of mice exposed to air or whole body cigarette smoke twice daily during 5 days. The mice received vehicle (PBS) or VPA (100 µg/70 µl PBS) by oropharyngeal aspiration 15 minutes prior to air/smoke exposure. (D) acPGP was measure in the BAL fluid. (E) PE activity was measured in the BAL fluid and compared to control (PBS treated/air exposed mice). N = 5–10 animals per group. Values are expressed as mean+/−S.E.M. **P≤0.01, ***P≤0.001, ns p>0.05.