Skip to main content
. 2014 May 16;9(5):e97262. doi: 10.1371/journal.pone.0097262

Table 1. Baseline characteristics of the patients.

Group A Group B
(n = 242) (n = 45)
Male, no. (%) 183 (75.6) 34 (75.6)
Age, years, M (range) 44 (21–81) 42 (25–67)
Weight, kg, M (range) 69 (45–139) 67 (49–116)
Risk factor for HIV, no. (%)
Previous iv drug use 80 (33.0) 14 (31.1)
Hetero/homosexual 154 (63.6) 29 (64.4)
Other 8 (3.3) 2 (4.4)
Methadone treatment, no. (%) 30 (12.3) 8 (17.7)
Nadir CD4/µl, M (range) 198 (4–762) 218 (6–480)
Clinical category C, no. (%) 57 (23.5) 9 (20.0)
Chronic hepatitis/cirrhosis, no. (%) 69 (28.5)/21 (8.6) 8 (17.7)/5 (11.1)
HCV 81 (90.0) 9 (69.2)
HBV 5 (5.5) 1 (7.6)
HCV+HVB 2 (14.3)
Other 3 (3.3) 2 (14.3)
No. previous ART, M (range) 2 (1–9) 2 (1–7)
Months on previous ART, M (range) 36 (1–186) 37 (3–168)
Previous antiretroviral regimen, no. (%)
EFV +2 NRTIs 134 (55.3) 38 (84.4)
NVP +2 NRTIs 16 (6.6) 7 (15.5)
IP/rtv +2 NRTIs 87 (35.9)
3 NRTIs 5 (2.0)
Previous failure on NNRTIs, no. (%) 45 (100)
Available genotypic resistance test, no. (%) 137 (56.6) 45 (100)
Wild type 124 (90.5) 17 (37.8)
K103N 22 (48.9)
L100I or K101E or V179T 3 (6.6)
G190A 2 (4.4)
CD4/µl, M (range) 473 (12–1360) 468 (31–1351)
HIV-RNA copies/ml, M (range) <50 (<50–444867) 982 (108–170000)
HIV-RNA <50 copies/ml, no. (%) 179 (74.0)
Associated NRTIs, no. (%)
TDF+FTC 146 (60.3) 22 (48.9)
ABV +3TC 83 (34.3) 9 (20.0)
AZT+TDF 5 (2.1) 10 (22.2)
ABV+TDF 5 (2.1) 2 (4.4)
AZT +3TC 2 (0.8)
ddI +3TC 1 (0.4) 2 (4.4)
ETR 400 mg qd, no. (%) 215 (88.8) 29 (64.4)

ART: antiretroviral treatment. NRTIs: nucleos(t)ide reverse-transcriptase inhibitors. NNRTIs: non-nucleoside reverse-transcriptase inhibitors. EFV: efavirenz. NVP: nevirapine. TDF: tenofovir. FTC: emtricitabine. ABV: abacavir. 3TC: lamivudine. AZT: zidovudine.