Skip to main content
. 2014 May 16;9(5):e97798. doi: 10.1371/journal.pone.0097798

Figure 1. Age-associated risk factors for UTI in nulliparous virgin hosts.

Figure 1

Organ weight-adjusted bladder CFU for UPEC (A) and GBS (B), and kidney CFU for UPEC (C) and GBS (D) at 24 hours post infection of C3H/HeN female mice with ∼107 UPEC UTI89 alone or with ∼107 GBS COH1 in UPEC+GBS mixed inoculation. N = 1–4, at least 5 mice per experiment, where N indicates the number of biologically distinct experiments performed (N = 4 for 7–9wk groups, N = 1 for UPEC mono-infected 7–11mo group, and N = 2 for GBS mono-infected and all dual-infected 7–11mo groups). Recovered titers of zero were set to the limit of detection of the assay for statistical analyses and graphical representation in all figures. The horizontal bar represents the median value for each group of mice. Statistical significance was determined by the Kruskal-Wallis test with Dunn’s post-test for multiple comparisons. * P<0.05, ** P<0.005, *** P<0.0005.