Figure 3. Multiparity-associated augmentation of UPEC cystitis is blunted in C3H/HeJ mice.

UPEC CFU in bladders (A) and kidneys (B) were determined 24 hours after mono- or dual-species infection in 7–11 month old multiparous C3H/HeN and C3H/HeJ mice. N = 2–4, at least 5 mice per experiment. The horizontal bar represents the median value for each group of mice. Statistical significance was determined by the Kruskal-Wallis test with Dunn’s post-test for multiple comparisons. * P<0.05, ** P<0.005.