Figure 2. Whole body DXA results at 12 and 24 weeks for WT and cKO male mice.
(A) Body weight was significantly reduced in the Osx-Cre cKO and unchanged for VEC-Cre mice. (B) Percent fat was not significantly reduced in the 12- and 24week old Osx-Cre cKO male mice (although it did reach significance at 24 weeks when male and female data were pooled (ANOVA)). (C) Osx-Cre cKO male mice showed a significant reduction in BMC at the 12-week time point, with a non-significant trend at 24 weeks (which was significant when male and female data were pooled (ANOVA)). BMC was unchanged for VEC-Cre mice at either time point.