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(Osx-Cre data shown at 12 weeks, VEC-Cre data shown at 16 weeks.) Osx-Cre cKO mice had (A) shorter tibia and (B) reduced cortical bone volume with no change in (C) cancellous BV/TV or (D) cortical TMD. VEC-Cre mice showed no differences in any parameter. (E) Illustrations of cortical bone geometry show a smaller marrow cavity in the Osx-Cre cKO mice.
