Table 2.
Infant CD4, CD19 and CD8 parameters at 2 months of age
| Maternal viral load | CD4 (mean, 95% CI) | p † | Adjusted CD4 (mean, 95% CI) | p ‡ | CD19 (mean, 95% CI) | p † | Adjusted CD19 (mean, 95% CI) | p ‡ | CD8 (mean, 95% CI) | p † | Adjusted CD8 (mean, 95% CI) | P ‡ | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
>1000 |
Relative* |
44.3 (41.5–47.0) |
0.007 |
43.5 (40.6–46.3) |
0.001 |
28.7 (26.1–31.4) |
0.003 |
29.3 (26.4–32.2) |
0.001 |
15.5 (14.0–17.1) |
0.90 |
16.0 (14.4–17.6) |
0.58 |
| |
Absolute** |
2432 (2072–2792) |
0.02 |
2395 (2009–2781) |
0.022 |
1479 (1255–1703) |
0.79 |
1510 (1272–1747) |
0.49 |
849 (713–985) |
0.26 |
868 (721–1015) |
0.94 |
|
50–1000 |
Relative |
48.7 (46.2–51.3) |
0.74 |
48.6 (46.1–51.0) |
0.99 |
23.8 (21.3–26.4) |
0.65 |
24.2 (21.7–26.7) |
0.96 |
15.8 (14.4–17.2) |
0.68 |
15.6 (14.2–17.0) |
0.73 |
| |
Absolute |
2872 (2533–3210) |
0.94 |
2888 (2548–3229) |
0.96 |
1375 (1165–1585) |
0.53 |
1416 (1206–1625) |
0.57 |
952 (824–1079) |
0.77 |
947 (817–1077) |
0.80 |
|
<50 |
Relative |
48.3 (47.3–49.2) |
Ref |
48.5 (47.6–49.5) |
Ref |
24.5 (23.5–25.4) |
Ref |
24.1 (23.2–25.1) |
Ref |
15.4 (14.9–16.0) |
Ref |
15.5 (15.0–16.1) |
Ref |
| Absolute | 2884 (2759–3010) | 2878 (2751–3005) | 1446 (1369–1523) | 1419 (1342–1497) | 931 (884–979) | 930 (882–979) |
*Relative counts are reported as percentages.
**Absolute counts are reported as cells/mm3.
†Comparing means in group VL > 1000 and VL 50–1000 to VL < 50 (reference group) using sum of least squares.
‡Adjusted for maternal CD4, maternal ART use, infant ART use, gender, gestational age and race in a multivariable analysis of variance.