Table 3.
Infant CD4, CD19 and CD8 parameters at 6 months of age
| Maternal viral load | CD4 (mean, 95% CI) | p † | Adjusted CD4 (mean, 95% CI) | p ‡ | CD19 (mean, 95% CI) | p † | Adjusted CD19 (mean, 95% CI) | p ‡ | CD8 (mean, 95% CI) | p † | Adjusted CD8 (mean, 95% CI) | P ‡ | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| >1000 |
Relative* |
42.1 (39.3–44.9) |
0.009 |
40.1 (37.1–43.1) |
<0.001 |
30.8 (27.9–33.7) |
0.008 |
32.9 (29.8–36.1) |
<0.001 |
15.2 (13.6–16.8) |
0.99 |
14.9 (13.2–16.6) |
0.73 |
| |
Absolute** |
2271 (1907–2635) |
0.002 |
2290 (1893–2687) |
0.022 |
1528 (1261–1794) |
0.27 |
1712 (1420–2003) |
0.73 |
828 (680–977 |
0.10 |
853 (690–1016) |
0.95 |
| 50-1000 |
Relative |
47.0 (44.5–49.4) |
0.52 |
46.8 (44.3–49.2) |
0.78 |
27.0 (24.5–29.6) |
0.75 |
27.8 (25.2–30.4) |
0.27 |
15.8 (14.4–17.1) |
0.43 |
15.3 (13.9–16.7) |
0.24 |
| |
Absolute |
2861 (2540–3181) |
0.88 |
2876 (2550–3202) |
0.96 |
1727 (1492–1961) |
0.76 |
1788 (1549–2027) |
0.32 |
937 (806–1068) |
0.74 |
926 (792–1060) |
0.68 |
| <50 |
Relative |
46.1 (45.1 – 47.1) |
Ref |
46.4 (45.4–47.4) |
Ref |
26.6 (25.5–27.6) |
Ref |
26.2 (25.2–27.3) |
Ref |
15.2 (14.6–15.7) |
Ref |
15.3 (14.7–15.8) |
Ref |
| Absolute | 2887 (2756–3017) | 2878 (2747–3010) | 1687 (1592–1783) | 1656 (1559–1752) | 961 (908–1014) | 957 (903–1011) |
*Relative counts are reported as percentages.
**Absolute counts are reported as cells/mm3.
†Comparing means in group VL > 1000 and VL 50–1000 to VL < 50 (reference group) using sum of least squares.
‡Adjusted for maternal CD4, maternal ART use, infant ART use, gender, gestational age and race in a multivariable analysis of variance.