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. Author manuscript; available in PMC: 2014 May 17.
Published in final edited form as: J Biopharm Stat. 2014;24(4):817–833. doi: 10.1080/10543406.2014.901341

Table 2.

One-sided Boundaries for the 5th Analysis zc(5) When α = 0.025 and K = 5 (The test parameter is assumed to be β1 for j = 1 − 4, β2 for j = 5, where j = 1,, 5, tj=j/5.)

Alpha Spending Function w
1 0.8 0.5 0 −0.5 −0.7
O’Brien-Fleming Like Function, α1(t*) 2.03 2.13 2.19 2.23 2.23 2.23
Pocock Like Function, α2(t*) 2.39 2.54 2.64 2.70 2.70 2.70