Table 5.
The comparison of SLE patients with and without pulmonary fibrosis
| Parameter | SLE with pulmonary fibrosis (n = 17) | SLE without pulmonary fibrosis (n = 17) | p value |
|---|---|---|---|
| SLAM | 8.00 ± 3.17 | 6.00 ± 2.31 | p = 0.01 |
| Time of SLE duration (years) | 11.00 ± 8.16 | 5.00 ± 6.33 | ns (p = 0.42) |
| Lymphocytes % BALF | 20.82 ± 12.27 | 16.00 ± 8.27 | ns (p = 0.29) |
| Eosinophils % BALF | 0.00 ± 1.94 | 1.00 ± 1.3 | ns (p = 0.07) |
| Neutrophils % BALF | 2.00 ± 8.02 | 1.00 ± 2.02 | ns (p = 0.37) |
| Macrophages % BALF | 81.00 ± 14.84 | 80.00 ± 8.04 | ns (p = 0.19) |
| FEV1/FVC (%) | 82.37 ± 8.14 | 85.50 ± 4.94 | ns (p = 0.25) |
| FEV1 (%pred.) | 90.50 ± 21.09 | 100.00 ± 16.59 | ns (p = 0.09) |
| FVC (%pred.) | 93.26 ± 22.44 | 106.00 ± 15.09 | ns (p = 0.27) |
| TLC (%pred.) | 88.00 ± 28.29 | 112.00 ± 21.08 | p = 0.01 |
| DLCOc (%pred.) | 90.00 ± 28.32 | 98.00 ± 15.72 | ns (p = 0.43) |
| IL-8 BALF (pg/ml) | 41.3 ± 59.48 | 28.06 ± 121.23 | ns (p = 0.42) |
| IL-8 EBC (pg/ml) | 3.92 ± 0.39 | 3.78 ± 0.63 | ns (p = 0.89) |
Values are given as the mean ± SD
BALF bronchoalveolar lavage fluid, DLCOc diffusion capacity for carbon monoxide corrected for hemoglobin concentration, EBC exhaled breath condensate, FEV 1 forced expiratory volume in 1 s, FVC forced vital capacity, ns not significant, SLAM systemic lupus activity measure, TLC total lung capacity, %pred. % predicted