Table 6.
The comparison of SLE patients in relation to immunosuppressive treatment
| Parameter | With immunosuppressive treatment (n = 16) | Without immunosuppressive treatment (n = 18) | p value |
|---|---|---|---|
| SLAM | 8.00 ± 3.87 | 7.00 ± 1.90 | ns (p = 0.35) |
| Time of SLE duration (years) | 6.00 ± 6.27 | 8.00 ± 8.49 | ns (p = 0.63) |
| Lymphocytes % BALF | 16.00 ± 10.30 | 17.00 ± 10.10 | ns (p = 0.79) |
| Eosinophils % BALF | 0.00 ± 0.89 | 1.00 ± 2.09 | ns (p = 0.052) |
| Neutrophils % BALF | 2.50 ± 7.82 | 1.0 ± 3.77 | ns (p = 0.41) |
| Macrophages % BALF | 80.00 ± 11.13 | 82.00 ± 13.41 | ns (p = 0.81) |
| FEV1/FVC (%) | 82.20 ± 6.96 | 85.00 ± 6.69 | ns (p = 0.29) |
| FEV1 (%pred.) | 90.13 ± 25.25 | 100.00 ± 12.76 | ns (p = 0.29) |
| FVC (%pred.) | 97.50 ± 25.13 | 107.00 ± 12.73 | ns (p = 0.53) |
| TLC (%pred.) | 88.50 ± 36.35 | 97.00 ± 11.82 | ns (p = 0.31) |
| DLCOc (%pred.) | 99.00 ± 31.37 | 90.00 ± 13.38 | ns (p = 0.14) |
| IL-8 BALF (pg/ml) | 49.42 ± 135.00 | 29.63 ± 18.07 | ns (p = 0.07) |
| IL-8 EBC (pg/ml) | 3.82 ± 0.42 | 3.82 ± 0.63 | ns (p = 0.64) |
Values are given as the mean ± SD
BALF bronchoalveolar lavage fluid, DLCOc diffusion capacity for carbon monoxide corrected for hemoglobin concentration; EBC exhaled breath condensate, FEV 1 forced expiratory volume in 1 s, FVC forced vital capacity, ns not significant, SLAM systemic lupus activity measure, TLC total lung capacity, %pred. % predicted