Table 1.

Participants demographics

Participants	Untreated	Treated	p value
N = 44	N = 19	N = 25
Mean Age (SD), year	75.8 (6.9)	76.2 (5.1)	0.81
Age range, year	64-88	65-84
Sex, %Male	42.1	48.0	0.77
Mean Education (SD), year	14.7 (2.9)	14.7 (2.8)	1.00
Mean MMSE (SD)	25.5 (3.7)	26.5 (3.1)	0.33
CDR (No. of 0.5/1)	16/3	21/4	1.00
Mean CDR sum of boxes (SD)	2.3 (1.6)	2.8 (1.5)	0.25
APOE genotype, % ε4+	57.9	64.0	0.76

SD: standard deviation, MMSE: mini-mental state examination, for which the range of scores is from 30 (“best”) to 0 (“worst”), CDR: Clinical Dementia Rating, for which CDR 0.5 and CDR 1 indicate very mild and mild AD respectively, the CDR sum of boxes (the sum of individual CDR domain scores) range from 0 to 18, with lower scores indicating better performance. APOE: Apolipoprotein E