Supplementary Fig. 4.

Parameters of the linear fit to PD* in gray matter masked areas defined by the AAL atlas that showed significant change with age. PD* at the age of 25 years is shown in (A) and the rate of increase (green, purple) or decrease (blue, red) of PD* with age is shown in (B). The ROIs are ordered from left to right with decreasing percentage of ROI that significantly correlated with age. The mean percentage (across hemispheres) of the ROIs with more than 10% of constituent voxels showing a negative correlation with age are noted. No positive correlation had more than 1.2% of consituent voxels showing significance. The peak tscore within the ROIs ranged from 5.5 to 11.8. Abbreviations: AAL, automated anatomical labeling; ROI, region of interest.