Figure 1.

Behavioural disruptions vary across preference, general social and neutral activity measures. (a) MK-801 females (n = 10) had lower post-treatment preference than controls (n = 10), but (b) overall activity levels (sum of all three general social and three neutral behaviours; table 1) were not altered. However, the character of activity changed, with a shift from social (general approach behaviours directed towards either stimulus zone regardless of stimulus ID) towards neutral (behaviours not directed towards either stimulus zone). (c) The ratio of social to neutral behaviours ((sum of three social behaviours)/(sum of three neutral behaviours)) was lower in post-trials for MK-801 females but not controls. ‘Preference’ represents biased measures towards one stimulus over another (see table 1 for behavioural definitions). Box plots indicate first and third quartiles, the line indicates the median and whiskers indicate high and low values. Circles denote outliers. (Online version in colour.)