Table 4. Hazard ratios (HR) and 95% Confidence Intervals (CI) for Incident AF by LV mass.

Measure	HR (95% CI)
	Model 1* Unadjusted	P-value	Model 2† Multivariable-adjusted*	P-value
CMR-derived
LV mass†‡	1.50 (1.34, 1.687)	<0.001	1.45 (1.23, 1.70)	<0.001
LV mass (intervals)
≤50th percentile	1 (ref.)		1 (ref.)
50th - 90th percentile	1.33 (0.84, 2.10)	0.21	1.23 (0.76, 2.00)	0.39
90th - 95th percentile	1.55 (0.99, 2.43)	0.05	1.29 (0.76, 2.20)	0.33
>95th percentile	2.77 (1.84, 4.16)	<0.001	2.04 (1.15, 3.62)	0.015
ECG-derived‡
LV mass†	1.33 (1.17, 1.52)	<0.001	1.01 (0.75, 1.36)	0.11
LV mass (intervals)
≤50th percentile	1 (ref.)		1 (ref.)
50th - 90th percentile	1.87 (1.18, 2.95)	0.007	1.39 (0.84, 2.31)	0.19
90th - 95th percentile	1.93 (1.22, 3.05)	0.005	0.99 (0.54, 1.83)	0.99
>95th percentile	2.67 (1.73, 4.12)	<0.001	1.31 (0.61, 2.81)	0.47

^*Adjusted for cardiovascular risk factors (age, sex, ethnicity, weight, height, systolic BP, diabetes, total and HDL cholesterol, smoking, and hypertension/lipid/arrhythmia/digitalis medication

^†Standardized (centered at 0 and scaled to SD units)

^‡ECG-LV mass derived from Rautaharju models