Table 5. Hazard ratios (HR) and 95% Confidence Intervals (CI) for Incident AF by ECG-LVH criteria.
| ECG measure | HR (95% CI) | |||||
|---|---|---|---|---|---|---|
|
| ||||||
| Model 1* | P-value | Model 2† | P-value | Model 3‡ | P-Value | |
|
|
||||||
| Voltage-only criteria | ||||||
| Sokolow-Lyon voltage | 1.97 (1.36, 2.80) | <0.001 | 1.57 (1.06, 2.32) | 0.02 | 1.37 (0.92, 2.07) | 0.12 |
| Cornell voltage | 1.49 (0.81, 2.73) | 0.19 | 1.36 (0.72, 2.58) | 0.33 | - | - |
| Framingham adjusted Cornell voltage | 1.48 (0.80, 2.72) | 0.20 | 1.36 (0.76, 2.58) | 0.33 | - | - |
| Minnesota code 3.1 | 1.65 (1.01, 2.69) | 0.04 | 1.26 (0.76, 2.08) | 0.35 | - | - |
| Lewis index | 1.02 (0.68, 1.54) | 0.89 | 0.72 (0.47, 1.11) | 0.14 | - | - |
| Gubner and Ungerleider | 1.45 (0.89, 2.36) | 0.12 | 1.02 (0.62, 1.68) | 0.91 | - | - |
| Voltage-duration product | ||||||
| Sokolow-Lyon voltage product | 2.56 (1.56, 4.21) | <0.001 | 2.24 (1.33, 3.76) | 0.002 | 1.83 (1.06, 3.14) | 0.02 |
| Cornell voltage product | 1.97(1.28, 3.04) | 0.002 | 1.69 (0.94, 2.31) | 0.09 | - | - |
| Composite criteria | ||||||
| Romhilt-Estes score ≥ 4 | 2.45 (1.08, 5.53) | 0.03 | 1.48 (0.64, 3.39) | 0.94 | - | - |
| Perugia score | 2.07 (1.28, 3.32) | 0.003 | 1.71 (1.09, 2.81) | 0.03 | 1.35(0.7 9, 2.28) | 0.26 |
|
| ||||||
| Perugia 2 score | 1.83 (1.10, 3.06) | 0.020 | 1.38 (0.80, 2.38) | 0.25 | - | - |
*
Unadjusted
†
Adjusted for cardiovascular risk factors (age, sex, ethnicity, weight, height, systolic BP, diabetes, total and HDL cholesterol, smoking, and hypertension/lipid/arrhythmia/digitalis medication
‡
Adjusted for cardiovascular risk factors (age, sex, ethnicity, weight, height, systolic BP, diabetes, total and HDL cholesterol, smoking, hypertension/lipid/arrhythmia/digitalis medication and CMR-LVH)