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. Author manuscript; available in PMC: 2015 Jun 1.
Published in final edited form as: Chem Asian J. 2014 Mar 12;9(6):1446–1472. doi: 10.1002/asia.201301693

Figure 20.

Figure 20

(A) Guanine derivatives self-assemble to G-quartets in the presence of metal ions K+. Hydrogel formed from 77. (B) Picture showing that the sample does not flow when the vial is inverted at 15 mM, 23°C in 0.5 M sodium acetate buffer at pH 6.0. (C) TTEM images of fibers forming the gel. (D) Controlled release profiles from the hydrogel formed by 77 as determined by 1H NMR spectroscopy for (■) Acyclovir (553%), (○) Vitamin C (553%), (▲) Vancomycin (393%), (×) Guanosine-5′-hydrazide 77 (73%). (Adapted from © 2005 by the National Academy of Sciences of the USA with permission.[131])