Fig. 1.

Correlation of mutational load (ML) to histological classification of microdissected targets a based on the presence and extent of low and high clonality LOH mutations only (correlation coefficient = 0.68, p < 0.0001) and b based on the presence and extent of low and high clonality LOH mutations as well as MSI (correlation coefficient = 0.69, p < 0.0001). COL columnar mucosa, IM intestinal metaplasia, IND indefinite for dysplasia, LGD low-grade dysplasia, HGD high-grade dysplasia, EAC esophageal adenocarcinoma