Table 1.
Average number of mutations detected in microdissected targets with each histology
| Histological classification | Total micro. targets tested | Average number of mutated loci detected per micro. target | Average number of low/high clonality LOH and MSI mutations detected per micro. target | Average mutational load (ML) | ||
|---|---|---|---|---|---|---|
| Low | High | MSI | ||||
| COL | 99 | 0.5 | 0.5 | 0.0 | 0.0 | 0.3 |
| IM | 427 | 1.1 | 0.7 | 0.1 | 0.3 | 0.7 |
| IND | 182 | 1.9 | 1.4 | 0.3 | 0.2 | 1.1 |
| LGD | 85 | 2.7 | 1.7 | 0.6 | 0.5 | 1.8 |
| HGD | 61 | 4.3 | 2.2 | 1.6 | 0.8 | 3.2 |
| EAC | 23 | 5.9 | 4.3 | 1.3 | 0.8 | 3.9 |
COL columnar mucosa, IM intestinal metaplasia, IND indefinite for dysplasia, LGD low-grade dysplasia, HGD high-grade dysplasia, EAC esophageal adenocarcinoma, Micro. microdissected