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. 2014 Jun;20(6):882–898. doi: 10.1261/rna.041822.113

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© 2014 Wu et al.; Published by Cold Spring Harbor Laboratory Press for the RNA Society

This article is distributed exclusively by the RNA Society for the first 12 months after the full-issue publication date (see http://rnajournal.cshlp.org/site/misc/terms.xhtml). After 12 months, it is available under a Creative Commons License (Attribution-NonCommercial 4.0 International), as described at http://creativecommons.org/licenses/by-nc/4.0/.

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FIGURE 6. — Evaluating the virulence of sRNA deletion mutants in a zebrafish model. Zebrafish were challenged with wild-type strain P1/7, sRNA deletion mutants, and sRNA complemented strains. The LD₅₀ was calculated to compare the virulence of strains. An unpaired t-test was used to compare log₁₀LD₅₀ between strains P1/7 and Δrss12. For the remaining comparisons, statistical analyses were performed using one-way ANOVA and Dunnett's multiple comparisons test. (*) P< 0.05, (**) P< 0.01. C-rss03, C-rss04, C-rss05, C-rss06, and C-rss11 denote the complemented strains for rss03, rss04, rss05, rss06, and rss11, respectively.