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. 2014 Mar 19;306(10):F1198–F1209. doi: 10.1152/ajprenal.00699.2013

Fig. 1.

Fig. 1.

Changes in podocyte number in aging nephropathy. Ren1cCre × Rs-ZsGreen-R reporter mice were studied with advancing age at 4, 12, 52 and 64 wk. A: glomerular tuft area increased progressively and significantly at 52 and 64 wk of age. B: podocyte density, measured by the number of p57-stained cells/glomerular tuft area was significantly reduced at 52 and 64 wk compared with younger ages. C–F: examples of p57 staining (brown, nuclear) at ages 4 (C), 12 (D), 52 (E), and 64 (F) wk respectively.